The Karma Oncology team is experienced in managing oncology trials in many different tumour types and using different therapeutic approaches.


Tumour Types

  • Acute myeloid leukaemia
  • Breast cancer
  • Breast cancer with bone metastases
  • Cancer with bone metastases
  • Colorectal cancer
  • Endometrial cancer
  • Gastric Cancer
  • Glioblastoma Cancer
  • Head & Neck Cancer
  • Hepatocellular cancer
  • Hypercalcaemia of malignancy
  • Lymphoma
  • Malignant melanoma
  • Mesothelioma
  • Metastatic colon cancer
  • Multiple myeloma
  • Non-small cell lung cancer
  • Ovarian cancer
  • Pancreatic cancer
  • Prostate cancer
  • Renal cell cancer
  • Small cell lung cancer
  • Solid tumours
  • Thyroid Cancer


Therapeutic Approaches

  • Cell therapies
  • Gene therapies
  • Immunotherapies
  • Oral and i.v. cytotoxic agents
  • Cytostatic agents
  • Targeted therapies
  • Hormonal therapies
  • Monoclonal antibodies
  • Selective internal radiation
  • Devices
  • Palliative care therapies
  • CAR-T therapies

Some Recent Assignments and Achievements:

  • Full clinical development planning for small biotech company which included protocol synopses (phases 1, 2 and 3), timelines and budgets to allow the sponsor to obtain funding from investors and implement their first trial
  • European monitoring and project management for a FIH study for a US sponsor
  • Protocol design and site selection for hepatic and pancreatic cancer trials using radioactive beads that are implanted directly into tumours
  • Protocol design and writing for a phase I/II breast cancer trial
  • Data cleaning for phase 1 solid tumour trial
  • Project management for global phase 3 pancreatic cancer study
  • Project management of phase 2 non-small cell lung cancer trial
  • Project management of a pivotal phase 3 study – we brought recruitment in 3 months ahead of schedule and locked the database within 5 days of LSLV.





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