The Karma Oncology team is experienced in managing oncology trials in many different tumour types and using different therapeutic approaches.

Tumour Types
- Acute myeloid leukaemia
- Breast cancer
- Breast cancer with bone metastases
- Cancer with bone metastases
- Colorectal cancer
- Endometrial cancer
- Gastric Cancer
- Glioblastoma Cancer
- Head & Neck Cancer
- Hepatocellular cancer
- Hypercalcaemia of malignancy
- Lymphoma
- Malignant melanoma
- Mesothelioma
- Metastatic colon cancer
- Multiple myeloma
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
- Renal cell cancer
- Small cell lung cancer
- Solid tumours
- Thyroid Cancer
Therapeutic Approaches
- Cell therapies
- Gene therapies
- Immunotherapies
- Oral and i.v. cytotoxic agents
- Cytostatic agents
- Targeted therapies
- Hormonal therapies
- Monoclonal antibodies
- Selective internal radiation
- Devices
- Palliative care therapies
- CAR-T therapies

Some Recent Assignments and Achievements:
- Full clinical development planning for small biotech company which included protocol synopses (phases 1, 2 and 3), timelines and budgets to allow the sponsor to obtain funding from investors and implement their first trial
- European monitoring and project management for a FIH study for a US sponsor
- Protocol design and site selection for hepatic and pancreatic cancer trials using radioactive beads that are implanted directly into tumours
- Protocol design and writing for a phase I/II breast cancer trial
- Data cleaning for phase 1 solid tumour trial
- Project management for global phase 3 pancreatic cancer study
- Project management of phase 2 non-small cell lung cancer trial
- Project management of a pivotal phase 3 study – we brought recruitment in 3 months ahead of schedule and locked the database within 5 days of LSLV.
